It's time for another round of interleague play. The National League hosts 10 of the 14 interleague series that begin on Friday, but the American League will have the 10-4 home-field advantage next Friday for that weekend's round of games. Obviously this means that a number of AL designated hitters will be inactive when play begins this Friday. This interleague stuff would seem to be a significant disadvantage to AL clubs. The White Sox may have AL home run leader Jim Thome on the bench for more than one game against Cincinnati this weekend. Or they must sit Paul Konerko. Cleveland could be without Travis Hafner and Tampa Bay may be missing Jonny Gomes. Then again, not all NL clubs have a productive big league regular who suddenly gets more at-bats when they are on the road. Barry Bonds may play more when the Giants are in Seattle and San Diego's Mike Piazza may get some DH time this weekend. But NL teams often don't have a ninth bat that wil make a big difference. Does any of it make a difference? Well, the NL has a 22-20 record against the AL in this year's interleague play. The AL was 136-116 in 2005, but the NL has the all-time edge by a miniscule 1,126-1,116. Perhaps the DH issue doesn't matter, and the conventional wisdom that the AL is the better league may not stand up, as well. Or does the loss of the DH neutralize the talent difference between the two leagues?